Pathology Shared Resource

Director

• C. Harker Rhodes, MD, PhD Associate Professor, Pathology (C.Harker.Rhodes@Hitchcock.ORG)

Staff

• Steven Boyle, MHS, PA (ASCP) PSR Resource Coordinator                       (Steven.H.Boyle@Hitchcock.ORG)
• Eric York, PSR Histology Research Supervisor (Eric.B.York@Hitchcock.ORG)
• Susan Webber, BS, MT  Technical Specialist, Cell Processing Lab             (Susan.M.Webber@Hitchcock.ORG)

Contact Information

• E-mail:  Steven.H.Boyle@Hitchcock.ORG
• Website: http://researchpath.hitchcock.org/ResearchPathologyServices/

Mission

The Pathology Shared Resource (PSR) provides four primary services for NCCC investigators: (1) it partners researchers with appropriate pathologists to provide specific expertise matched to the needs of the research project; (2) it coordinates the procurement, preservation, and distribution of human tissues and cells for funded and developmental NCCC basic and clinical research; (3) it performs histologic, immunohistologic, and molecular diagnostic procedures for NCCC researchers; and (4) it provides a GMP cell processing laboratory for the isolation/purification, manipulation, expansion and/or storage of cells derived from a patient's/subject's peripheral blood intended for autologous reinfusion.

Services Provided

• Tissue Collection
  • Prospective fresh - immediate delivery
  • Prospective fresh - sterile
  • Prospective fresh - for frozen storage
  • Retrospective frozen tissue retrieval
  • Retrospective fixed tissue retrieval
• Histology Services
  • Slide retrieval - Retrospective
  • Process tissues for paraffin blocks
  • Slide preparation - H and E
  • Perform special stains
  • Immunohistochemistry
  • Sendout slides for protocol
• Clinical Pathology Services
  • Venipuncture
  • Chemistry
  • Hematology studies
  • Sendouts
  • Blood Bank
  • Flow
  • Chemistry
  • Microbiology
  • Cytogenetics
• Pathologist Consultation Services
  • Assistance with the collection of archived blocks to be used for your study
  • Slide interpretation
  • Assistance with the selection of stains or immunohistochemical antibodies to be used
  • Study design
  • Other professional services
• Research Resources
  • Laser capture dissection microscopy
  • Cell radiolabeling for survival, traffic and localization studies
  • Apheresis collections of peripheral blood fractions
  • Processing, stimulation and selection of cell populations from peripheral blood collections

Facility

The Pathology Shared Resource is closely integrated with the anatomic pathology laboratory of Mary Hitchcock Memorial Hospital and provides a cost-effective mechanism for NCCC investigators to take advantage of the economic efficiencies provided by that high-volume facility. The Core is managed by the Norris Cotton Cancer Center as a shared resource on behalf of the university and is available to all investigators within the greater Dartmouth research community. This Shared Resource is supported by funds from the Norris Cotton Cancer Center Core Grant is overseen by the EMTG, an oversight and advisory committee of the Cancer Center.

Charges

Most services of this shared resource are on a fee-for-service basis.  Charges for services will be made directly to investigator accounts.